C4282

Coenzyme A hydrate

≥85% (UV, HPLC)

• Synonyme(s) : CoA
• Formule empirique (notation de Hill) : C₂₁H₃₆N₇O₁₆P₃S · xH₂O
• Numéro CAS: 85-61-0
• Poids moléculaire : 767.53 (anhydrous basis)
• UNSPSC Code: 12352100
• NACRES: NA.21
• PubChem Substance ID: 24892684
• MDL number: MFCD06795839
• Beilstein/REAXYS Number: 77809

Propriétés

• biological source: yeast
• Quality Segment: 200
• assay: ≥85% (UV, HPLC)
• form: powder
• functional group: phospholipid
• shipped in: dry ice
• storage temp.: −70°C
• SMILES string: O.CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n2cnc3c(N)ncnc23)[C@@H](O)C(=O)NCCC(=O)NCCS
• InChI: 1S/C21H36N7O16P3S.H2O/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);1H2/t11-,14-,15-,16+,20-;/m1./s1
• InChI key: TVSAELAFGDOPKI-BLPRJPCASA-N

Description

Application

Coenzyme A hydrate has been used in the thiolase enzyme assay of recombinant acetoacetyl-CoA thiolase (rACAT) in Clonorchis sinensis. It may be used as a reference standard in Raman spectra measurements.

Biochem/physiol Actions

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP.

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.

Disclaimer

The free acid is less stable than the sodium or lithium salt; 5% decomposition may occur within 6 months when stored at −80 °C.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available