C0567

(−)-Catechin

from green tea, ≥97% (HPLC), powder, oxidative stress inhibitor

• Synonyme(s) : (−)-trans-3,3′,4′,5,7-Pentahydroxyflavane, (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
• Formule empirique (notation de Hill): C₁₅H₁₄O₆
• Numéro CAS: 18829-70-4
• Poids moléculaire : 290.27
• Numéro CE : 242-611-7
• Numéro MDL: MFCD00135997
• Code UNSPSC : 12352200
• ID de substance PubChem : 24892260
• Nomenclature NACRES : NA.77

Propriétés

• product name: (−)-Catechin, ≥97% (HPLC), from green tea
• Source biologique: green tea
• Pureté: ≥97% (HPLC)
• Forme: powder
• Température de stockage: 2-8°C
• Chaîne SMILES: O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3
• InChI: 1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
• Clé InChI: PFTAWBLQPZVEMU-HIFRSBDPSA-N
• Informations sur le gène: human ... BACE1(23621)

Description

Description générale

Catechins are major flavonoids present in green tea accounting to 90%. (−)-catechin is comparatively less bioavailable than the (+)-catechin for intestinal absorption.

Application

(-)-Catechin has been used:

• to test its binding affinity towards estrogen receptor
• as a reference standard in high-performance liquid chromatography for quantification of polyphenols from plant extracts (HPLC)
• as a reference standard in kinetic studies to quantify antioxidants from Iranian green tea leaves

Actions biochimiques/physiologiques

Catechins have wide biological functionality. They induce antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. It prevents fat accumulation.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)