C0399

Cromolyn sodium salt

≥95%, Mast cell stabilizer, powder

• Synonyme(s) : Cromoglycate, Cromoglycic acid
• Formule linéaire : C₂₃H₁₄O₁₁Na₂
• Numéro CAS: 15826-37-6
• Poids moléculaire : 512.33
• NACRES: NA.77
• PubChem Substance ID: 24892251
• UNSPSC Code: 12352200
• EC Number: 239-926-7
• MDL number: MFCD00057744
• Assay: ≥95%
• Form: powder

Propriétés

• Nom du produit: Cromolyn sodium salt, ≥95%
• Quality Segment: 200
• assay: ≥95%
• form: powder
• originator: Sanofi Aventis
• SMILES string: [Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O
• InChI: 1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;
• InChI key: UXMUBZWVLQEMRB-UHFFFAOYSA-N

Description

General description

Cromolyn sodium is a mast stabilizer, which is used to treat allergies. It is a bischromone and functions as a non-steroidal anti-inflammatory drug. It inhibits the release of histamines from mast cells.

Application

Cromolyn sodium salt has been used to block mast cell activation and to inhibit histamine secretion from rodent peritoneal mast cells. It has also been used to stabilize mast cells.

Biochem/physiol Actions

Cromolyn blocks the release of histamine and other pro-inflammatory mediators from mast cells.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves