A9899

Antazoline hydrochloride

• Synonyme(s) : 2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride
• Formule empirique (notation de Hill) : C₁₇H₁₉N₃ · HCl
• Numéro CAS: 2508-72-7
• Poids moléculaire : 301.81
• NACRES: NA.77
• PubChem Substance ID: 24277763
• UNSPSC Code: 12352200
• EC Number: 219-719-8
• MDL number: MFCD00058145
• Form: powder

Propriétés

• form: powder
• Quality Segment: 200
• originator: Novartis
• SMILES string: Cl.C1CN=C(CN(Cc2ccccc2)c3ccccc3)N1
• InChI: 1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H
• InChI key: SWKDMSRRIBZZAY-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

Biochem/physiol Actions

Imidazoline agonist; H₁ histamine receptor antagonist.

Imidazoline agonist; more potent than efaroxan in inducing insulin release from β cells; H₁ histamine receptor antagonist.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves