A7470
Anticorps anti-c-Myc
affinity isolated antibody
Synonyme(s) :
Anti-c-Myc
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.56
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Source biologique
rabbit
Niveau de qualité
Conjugué
agarose conjugate
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Espèces réactives
human
Classe(s) chimique(s) de l'analyte
proteins (c-Myc)
Technique(s)
affinity chromatography: suitable
immunoprecipitation (IP): suitable
Capacité
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
Numéro d'accès UniProt
Température de stockage
2-8°C
Informations sur le gène
human ... MYC(4609)
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Description générale
The human c-Myc proto-oncogene belongs to MYC oncogene family and is the human cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses. c-Myc gene is localized on human chromosome 8q24.21. The two major domains of include the N-terminal box regions and the C-terminal basic-region with helix-loop-helix/leucine-zipper motif.
Spécificité
Anti-c-Myc recognizes an epitope located on c-Myc tagged fusion proteins.
Immunogène
peptide synthétique de la protéine p62c-Myc humaine.
Application
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit has been used in:
- chromatin immunoprecipitation (ChIP)
- co-immunoprecipitation
- western blotting
- immunofluorescence
- immunoprecipitation
Actions biochimiques/physiologiques
c-Myc proto-oncogene increased expression is observed in a variety of human tumors. Amplification of Myc gene locus is observed in angiosarcomas and translocation is implicated in Burkitt′s lymphoma. c-Myc is a master regulator and targets a wide variety of metabolic events. An epitope located within amino acid residues 410-419 (EQKLISEEDL) of human c-Myc has been widely used as a tag in many expression vectors, enabling the expression of proteins as c-Myc tagged fusion proteins. Anti-c-Myc agarose is useful in the purification of expressed c-Myc tagged fusion proteins in bacterial lysates or transfected cells.
Forme physique
Suspension of beaded agarose (1:1 v/v) in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
Stockage et stabilité
For continuous use and extended storage, store at 2 °C to 8 °C. Do not freeze.
Clause de non-responsabilité
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Produit(s) apparenté(s)
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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