A6419

Adénosine 5′-triphosphate disodium salt hydrate

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• Synonyme(s) : ATP disodium salt
• Formule empirique (notation de Hill): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• Numéro CAS: 34369-07-8
• Poids moléculaire : 551.14 (anhydrous basis)
• Numéro MDL: MFCD00150755
• Code UNSPSC : 12352207
• eCl@ss : 32160414
• ID de substance PubChem : 24891086
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: microbial
• Niveau de qualité: 200
• Gamme de produits: BioReagent
• Pureté: ≥99% (HPLC)
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Solubilité: H₂O: 50 mg/mL
• Température de stockage: −20°C
• Chaîne SMILES: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Clé InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Description

Description générale

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Application

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

Actions biochimiques/physiologiques

Agoniste des récepteurs purinergiques P₂ ; augmente l′activité des canaux K⁺ activés par le Ca²⁺ ; substrat de systèmes d′enzymes dépendants de l′ATP

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type N95 (US)