69453

L-Homocysteine

≥98.0% (NT)

• Synonyme(s) : (S)-2-Amino-4-mercaptobutyric acid
• Formule linéaire : HSCH₂CH₂CH(NH₂)COOH
• Numéro CAS: 6027-13-0
• Poids moléculaire : 135.18
• NACRES: NA.32
• PubChem Substance ID: 329761669
• UNSPSC Code: 12352204
• EC Number: 227-891-0
• MDL number: MFCD00151320

Propriétés

• Nom du produit: L-Homocysteine, ≥98.0% (NT)
• Quality Segment: 100
• assay: ≥98.0% (NT)
• form: powder
• optical activity: [α]/D 25.5±1.5°, c = 1 in 1 M HCl
• color: white
• mp: 263-265 °C
• application(s): cell analysis
• relevant disease(s): Alzheimer′s disease
• storage temp.: −20°C
• SMILES string: N[C@@H](CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
• InChI key: FFFHZYDWPBMWHY-VKHMYHEASA-N

Description

General description

L-homocysteine is used to diagnose homocystinuria.

Application

L-homocysteine has been used as a supplement in cell culture media.

Biochem/physiol Actions

Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable