69453
L-Homocysteine
≥98.0% (NT)
Synonyme(s) :
(S)-2-Amino-4-mercaptobutyric acid
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Formule linéaire :
HSCH2CH2CH(NH2)COOH
Numéro CAS:
Poids moléculaire :
135.18
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352204
ID de substance PubChem :
Nomenclature NACRES :
NA.32
Produits recommandés
Nom du produit
L-Homocysteine, ≥98.0% (NT)
Essai
≥98.0% (NT)
Forme
powder
Activité optique
[α]/D 25.5±1.5°, c = 1 in 1 M HCl
Couleur
white
Pf
263-265 °C
Application(s)
cell analysis
Maladie(s) pertinente(s)
Alzheimer′s disease
Température de stockage
−20°C
Chaîne SMILES
N[C@@H](CCS)C(O)=O
InChI
1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
Clé InChI
FFFHZYDWPBMWHY-VKHMYHEASA-N
Description générale
L-homocysteine is used to diagnose homocystinuria.
Application
L-homocysteine has been used as a supplement in cell culture media.
Actions biochimiques/physiologiques
Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.
Conditionnement
Bottomless glass bottle. Contents are inside inserted fused cone.
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Assessment of homocysteine status
Refsum H, et al.
Journal of inherited metabolic disease, 20(2), 286-294 (1997)
Arpita Basu et al.
Atherosclerosis, 236(1), 188-195 (2014-07-27)
Plasma total homocysteine (tHcy) has been positively associated with carotid intima-media thickness (IMT) in non-diabetic populations and in a few cross-sectional studies of diabetic patients. We investigated cross-sectional and prospective associations of a single measure of tHcy with common and
K Mehlig et al.
Heart (British Cardiac Society), 99(23), 1761-1765 (2013-09-10)
An elevated level of total plasma homocysteine (tHcy) has been associated with risk of coronary heart disease (CHD). The level of tHcy is affected by lifestyle, in addition to genetic predisposition. The methylene tetrahydrofolate reductase (MTHFR) 677C>T polymorphism (rs1801133) is
Sanne Visser et al.
American journal of obstetrics and gynecology, 211(4), 373-373 (2014-03-19)
The aim of this study was to investigate which nonclassic cardiovascular biomarkers are associated with persistent endothelial dysfunction after pregnancy in women with a history of hypertensive pregnancy disorders compared with women with uncomplicated pregnancies. This was a systematic review
James J H Chong et al.
Journal of the American Heart Association, 8(1), e011028-e011028 (2019-01-01)
Background Neutrophil gelatinase-associated lipocalin ( NGAL ) or lipocalin 2 may promote atherosclerosis and plaque instability leading to increased risk of cardiac events. We investigated the relationships between plasma NGAL , cardiovascular disease biomarkers, and long-term cardiac events. Methods and
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique