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Merck
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49667

Sigma-Aldrich

4-(Maleinimido)phenyl isocyanate

purum, ≥97.0% (CHN)

Synonyme(s) :

N-(4-Isocyanatophenyl)maleimide, PMPI

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About This Item

Formule empirique (notation de Hill):
C11H6N2O3
Numéro CAS:
Poids moléculaire :
214.18
Numéro MDL:
Code UNSPSC :
12352106
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Qualité

purum

Niveau de qualité

Pureté

≥97.0% (CHN)

Forme

solid

Pertinence de la réaction

reagent type: linker

Pf

120-125 °C

Groupe fonctionnel

maleimide

Température de stockage

2-8°C

Chaîne SMILES 

O=C(C=C1)N(C(C=C2)=CC=C2N=C=O)C1=O

InChI

1S/C11H6N2O3/c14-7-12-8-1-3-9(4-2-8)13-10(15)5-6-11(13)16/h1-6H

Clé InChI

OJQSISYVGFJJBY-UHFFFAOYSA-N

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

A novel heterobifunctional linker for hydroxyl-to-thiol coupling

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Stéphane G Lévesque et al.
Bioconjugate chemistry, 18(3), 874-885 (2007-04-04)
Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-matrix (ECM) equivalents mimicking the degradation and remodeling of the ECM through the
Nileshi Saraf et al.
ACS omega, 4(1), 2234-2240 (2019-02-08)
A polydimethylsiloxane-based microfluidic device has been developed for the multiplex detection of viral envelope proteins such as Zika and chikungunya on a single platform using aptamer-analyte interactions. The channel is integrated with microsized pillars that increase the surface area allowing
Xiang Chen et al.
Clinical laboratory, 66(3) (2020-03-13)
Vitamin B12 is very important for the human body. Early diagnosis of vitamin B12 deficiency is essential because it is associated with many problems such as fatigue, lethargy, depression, poor memory, breathlessness, headaches, pale skin, mania, psychosis, etc. Most of
Alexis Loiseau et al.
Cancers, 11(12) (2019-12-11)
Nanohybrids based on titanate nanotubes (TiONts) were developed to fight prostate cancer by intratumoral (IT) injection, and particular attention was paid to their step-by-step synthesis. TiONts were synthesized by a hydrothermal process. To develop the customengineered nanohybrids, the surface of
M E Annunziato et al.
Bioconjugate chemistry, 4(3), 212-218 (1993-05-01)
p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then shown to be reactive with thiol-containing proteins. Examples include activation of vitamin B12, digoxigenin, digitoxigenin, estradiol

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