01930

Adenosine 5′-monophosphate disodium salt

≥99.0% (HPLC)

• Synonyme(s) : 5′-AMPdisodium salt,, Adenylic acid disodium salt, 5′-AMP-Na₂
• Formule empirique (notation de Hill): C₁₀H₁₂N₅Na₂O₇P
• Numéro CAS: 4578-31-8
• Poids moléculaire : 391.18
• Numéro Beilstein : 3586732
• Numéro CE : 224-961-2
• Numéro MDL: MFCD00065023
• Code UNSPSC : 41106305
• eCl@ss : 32160414
• ID de substance PubChem : 329747374
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: microbial (Candida utilis); synthetic
• Pureté: ≥99.0% (HPLC)
• Forme: powder
• Activité optique: [α]20/D −43±2°, c = 1% in 0.5 M Na₂HPO₄ (dry matter)
• Impuretés: ≤26% water
• Chaîne SMILES: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• Clé InChI: QGXLVXZRPRRCRP-IDIVVRGQSA-L

Description

Application

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase (EC 2.7.1.114), AMP deaminase (EC 3.5.4.6) and 5′-nucleotidase (EC 3.1.3.5).

Adenosine 5′-monophosphate disodium salt has been used:

• as a dissolved organic phosphorus (DOP) compound to study its rate of hydrolysis in Escherichia coli lysates
• to induce calcium responses in Fura2-loaded osteoblast (C2-OB)
• as a nucleotide metabolite in the medium for the isolation, culture, and identification of glioma stem cells (GSCs)

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)