496189

Chloroforme

biotech. grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Synonyme(s) : Trichlorométhane, Trichlorure de méthylidyne
• Formule empirique (notation de Hill): CHCl₃
• Numéro CAS: 67-66-3
• Poids moléculaire : 119.38
• Numéro Beilstein : 1731042
• Numéro MDL: MFCD00000826
• Code UNSPSC : 12191502
• ID de substance PubChem : 329757487
• Nomenclature NACRES : NA.04

Propriétés

• Qualité: biotech. grade
• Niveau de qualité: 100
• Densité de vapeur: 4.1 (vs air)
• Pression de vapeur: 160 mmHg ( 20 °C)
• Pureté: ≥99.8%
• Forme: liquid
• Contient: 0.5-1.0% ethanol as stabilizer
• Impuretés: <0.01% water
• Résidus d'évap.: <0.0003%
• Couleur: APHA: ≤10
• Indice de réfraction: n20/D 1.445 (lit.)
• pH: 5.2-6.4
• Point d'ébullition: 60.5-61.5 °C (lit.)
• Pf: −63 °C (lit.)
• Densité: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• Traces de cations: Pb: ≤0.05 ppm
• Chaîne SMILES: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• Clé InChI: HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

Description générale

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect. It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Low water content, minimal residue and clean UV spectra are the special characteristics of this biotech grade solvent. It can be utilized for biotechnological processes like protein sequencing, peptide and oligonucleotide synthesis. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.

Application

Chloroform may be used in the following processes:

• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
• Preparing phospholipid solutions.
• As a solvent in the photolysis reaction of ruthenium complexes.
• Solvent for recrystallization.
• Reference compound to detect the presence of chloroform in Tobacco smokes.
• Extractant in solvent extraction process.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372
• Conseils de prudence: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash