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T1900000

Triamcinolone acetonide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide, 9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide

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About This Item

Formule empirique (notation de Hill):
C24H31FO6
Numéro CAS:
76-25-5
Poids moléculaire :
434.50
Numéro MDL:
MFCD00056834
Code UNSPSC :
41116107
ID de substance PubChem :
329826694
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

triamcinolone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO

InChI

1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

Clé InChI

YNDXUCZADRHECN-JNQJZLCISA-N

Informations sur le gène

human ... NR3C1(2908)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Triamcinolone acetonide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H360

Classification des risques

Acute Tox. 4 Oral - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Fluocinolone acetonide European Pharmacopoeia (EP) Reference Standard

F0200000

Fluocinolone acetonide

Triamcinolone

Sigma-Aldrich

T6376

Triamcinolone

USP

USP

1679037

Triamcinolone acetonide Related Compound C

Budesonide ≥99%

Sigma-Aldrich

B7777

Budesonide

Tzu-Yun Kao et al.
American journal of ophthalmology, 156(1), 149-156 (2013-05-03)
To investigate the autofluorescence patterns of sealed macular holes and determine the correlations of the postoperative changes in spectral-domain optical coherence tomography and fundus autofluorescence (FAF) with the best-corrected visual acuity (BCVA) of patients with sealed idiopathic macular holes. Retrospective
Miriam Englander et al.
The British journal of ophthalmology, 97(4), 460-465 (2013-02-08)
To report the incidence rate of acute postoperative endophthalmitis secondary to therapeutic intravitreal injections. A retrospective review of all consecutive eyes after intravitreal injections was performed at the Massachusetts Eye and Ear Infirmary, Boston, from 1 January 2007 to 31
Marie-Hélène Errera et al.
Survey of ophthalmology, 58(2), 127-142 (2013-02-16)
Pregnancy-associated retinal diseases are conditions that may occur uniquely in pregnancy or, more commonly, general conditions that may worsen or alter during pregnancy as a result of hematologic, hormonal, metabolic, cardiovascular, and immunologic changes. Diabetic retinopathy (DR) is by far
Arthur Geltzer et al.
The Cochrane database of systematic reviews, 1(1), CD005022-CD005022 (2013-02-27)
Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangiogenic and anti-inflammatory properties. This review
Brian C Gilger et al.
Investigative ophthalmology & visual science, 54(4), 2483-2492 (2013-03-28)
To evaluate the effect of triamcinolone acetonide (TA) administered into the suprachoroidal space (SCS) using a microneedle and compare it with intravitreal (IVT) TA injections in a porcine model of acute posterior segment inflammation. An IVT injection of balanced salt
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