Needed to be recrystallized - MS showed contamination with Na.
S9876
Sulfathiazole
Synonyme(s) :
4-amino-N-2-thiazolylbenzènesulfonamide
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A propos de cet article
Formule empirique (notation de Hill) :
C9H9N3O2S2
Numéro CAS:
Poids moléculaire :
255.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-771-5
Beilstein/REAXYS Number:
226178
MDL number:
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analytical standard
Quality Segment
agency
EPA 1694
form
powder
technique(s)
HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
mp
200-202 °C (lit.)
application(s)
clinical testing
SMILES string
Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
InChI
1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
InChI key
JNMRHUJNCSQMMB-UHFFFAOYSA-N
General description
Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.
Biochem/physiol Actions
Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
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Cet article | |||
|---|---|---|---|
| description - | description European Pharmacopoeia (EP) Reference Standard | description VETRANAL®, analytical standard | description VETRANAL®, analytical standard |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) gas chromatography (GC): suitable, HPLC: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| application(s) clinical testing | application(s) pharmaceutical (small molecule) | application(s) clinical testing | application(s) clinical testing |
| form powder | form - | form - | form - |
| Quality Level 100 | Quality Level - | Quality Level 200 | Quality Level 100 |
| grade analytical standard | grade pharmaceutical primary standard | grade analytical standard | grade analytical standard |
| agency EPA 1694 | agency - | agency EPA 1694 | agency - |
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Mot-clé
Warning
Codes de danger
Mentions de précaution
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organes cibles
Respiratory system
Classe de stockage
11 - Combustible Solids
Que se passe-t-il ?
WGK 2
EPI (équipement de protection individuelle)
dust mask type N95 (US), Eyeshields, Gloves
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