LIGHTOX22

LightOx^™22

≥95% (HPLC)

• Formule empirique (notation de Hill) : C₂₂H₂₃NO₂
• Numéro CAS: 2324144-69-4
• Poids moléculaire : 333.42
• UNSPSC Code: 12352101
• NACRES: NA.22
• Assay: ≥95% (HPLC)
• Form: powder

Propriétés

• assay: ≥95% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: N1(CCC(c2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)(C)C)CC
• InChI: 1S/C22H23NO2/c1-4-23-14-13-22(2,3)19-15-17(9-12-20(19)23)6-5-16-7-10-18(11-8-16)21(24)25/h7-12,15H,4,13-14H2,1-3H3,(H,24,25)
• InChI key: JFQMWYKQDAWCSO-UHFFFAOYSA-N

Description

Application

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Biochem/physiol Actions

Strong ligand for retinoic acid receptor proteins

Features and Benefits

LightOx22 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx22 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Chemical Equivalency 1ea=1mg

Legal Information

LightOx is a trademark of LightOx Ltd.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable