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H1425000

Hydrocortisone hydrogen succinate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Hydrocortisone 21-hemisuccinate, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate, Cortisol 21-hemisuccinate

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About This Item

Formule empirique (notation de Hill):
C25H34O8
Numéro CAS:
2203-97-6
Poids moléculaire :
462.53
Numéro MDL:
MFCD00046256
Code UNSPSC :
41116107
ID de substance PubChem :
329815161
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

hydrocortisone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Conditions d'expédition

wet ice

Température de stockage

−20°C

Chaîne SMILES 

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]4(C)C[C@H](O)[C@H]23

InChI

1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

Clé InChI

VWQWXZAWFPZJDA-CGVGKPPMSA-N

Informations sur le gène

human ... NR3C1(2908)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrocortisone hydrogen succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1014

Hydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

1316004

Hydrocortisone, United States Pharmacopeia (USP) Reference Standard

1317007

Hydrocortisone 21-acetate, United States Pharmacopeia (USP) Reference Standard

1317302

Hydrocortisone butyrate, United States Pharmacopeia (USP) Reference Standard

1319002

Hydrocortisone hemisuccinate, United States Pharmacopeia (USP) Reference Standard

H1400000

Hydrocortisone 21-acetate, European Pharmacopoeia (EP) Reference Standard

H1300000

Hydrocortisone, European Pharmacopoeia (EP) Reference Standard

Y0001092

Hydrocortisone, European Pharmacopoeia (EP) Reference Standard

Y0001482

Hydrocortisone 21-acetate, European Pharmacopoeia (EP) Reference Standard

1321004

Hydrocortisone valerate, United States Pharmacopeia (USP) Reference Standard

1320001

Hydrocortisone phosphate triethylamine, United States Pharmacopeia (USP) Reference Standard

BP576

Hydrocortisone, British Pharmacopoeia (BP) Assay Standard

PHR1606

Hydrocortisone 21-acetate, Pharmaceutical Secondary Standard; Certified Reference Material

BP584

Hydrocortisone 21-acetate, British Pharmacopoeia (BP) Reference Standard

BP187

Hydrocortisone hydrogen succinate, British Pharmacopoeia (BP) Reference Standard

BP188

Hydrocortisone sodium phosphate, British Pharmacopoeia (BP) Reference Standard

PHR2160

Hydrocortisone Impurity J, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2157

Hydrocortisone Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2162

Hydrocortisone Impurity L, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2161

Hydrocortisone Impurity K, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2159

Hydrocortisone Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2163

Hydrocortisone Impurity M, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2158

Hydrocortisone Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2164

6a-Hydroxyhydrocortisone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2156

Hydrocortisone Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3185

Hydrocortisone Valerate, pharmaceutical secondary standard, certified reference material

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H360D

Classification des risques

Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Consulter la Bibliothèque de documents

Xiaolin Qi et al.
American journal of ophthalmology, 158(6), 1192-1198 (2014-08-20)
To investigate the morphologic changes and outcomes of the amniotic membrane as a carrier for allogeneic cultivated limbal epithelial transplantation. Prospective, noncomparative, interventional study. A total of 16 eyes receiving allogeneic cultivated limbal epithelial transplantation with amniotic membrane as a
Lucia Gagliardi et al.
The Journal of clinical endocrinology and metabolism, 99(11), 4149-4157 (2014-08-16)
Patients with Addison's disease (AD) report impaired subjective health status (SHS). Since cortisol exhibits a robust circadian cycle that entrains other biological clocks, impaired SHS may be due to the noncircadian cortisol profile achieved with conventional glucocorticoid replacement. Continuous subcutaneous
Takeshi Soma et al.
PloS one, 9(10), e110987-e110987 (2014-10-25)
We assessed the maintenance and distribution of epithelial stem/progenitor cells after corneal reconstruction using tissue-engineered oral mucosal cell sheets in a rat model. Oral mucosal biopsy specimens were excised from green fluorescent protein (GFP) rats and enzymatically treated with Dispase
Maureen Keller-Wood et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(4), R405-R413 (2014-06-13)
In normal pregnancy, cortisol increases; however, further pathological increases in cortisol are associated with maternal and fetal morbidities. These experiments were designed to test the hypothesis that increased maternal cortisol would increase maternal glucose concentrations, suppress fetal growth, and impair

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