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Merck

D7282

Desmethyldiazepam

analytical standard

Synonyme(s) :

Nordiazepam

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A propos de cet article

Formule empirique (notation de Hill) :
C15H11ClN2O
Numéro CAS:
Poids moléculaire :
270.71
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
214-123-4
MDL number:
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grade

analytical standard

Quality Segment

assay

≥98% (HPLC)

form

powder

drug control

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to light tan

solubility

DMSO: >10 mg/mL

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

room temp

SMILES string

Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)

InChI key

AKPLHCDWDRPJGD-UHFFFAOYSA-N

Gene Information

rat ... Tspo(24230)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Primary metabolite of diazepam; ligand for the GABAA receptor benzodiazepine modulatory site.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents



Pi Cheng et al.
Bioorganic & medicinal chemistry letters, 18(13), 3787-3789 (2008-06-06)
A series of 4-aryl-6-chloro-quinolin-2-ones and 5-aryl-7-chloro-1,4-benzodiazepine were synthesized and assayed for their in vitro anti-hepatitis B virus activities and cytotoxicities for the first time. Some of the tested compounds were active against HBsAg and HBeAg secretion in Hep G2.2.15 cells.
Joris C Verster et al.
Sleep medicine reviews, 17(2), 153-159 (2012-08-14)
The use of benzodiazepine receptor agonists can significantly impair driving performance. The aim of this review was to determine if there is a relation between blood concentrations of these drugs and the degree of driving impairment. A literature search was
Laura Mercolini et al.
Talanta, 80(1), 279-285 (2009-09-29)
Diazepam is frequently used as an adjuvant during antidepressant therapy. Recently, some studies have suggested that the treatment with benzodiazepines could have different efficacy in depressed patients as opposed to non-depressed ones. To clarify the matter, a study is currently



Numéro d'article de commerce international

RéférenceGTIN
D7282-25MG04061833588345
D7282-10MG04061833284674
D7282-5MG04061833284681