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D2954000

Dobutamine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C18H23NO3 · HCl
Numéro CAS:
49745-95-1
Poids moléculaire :
337.84
Numéro MDL:
MFCD00153795
Code UNSPSC :
41116107
ID de substance PubChem :
329798764
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

dobutamine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

Clé InChI

BQKADKWNRWCIJL-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB1(153) , ADRB2(154)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dobutamine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H312 + H332,H361fd

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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Jamshid Shirani et al.
The American journal of cardiology, 112(9), 1293-1297 (2013-07-23)
In patients with obstructive coronary artery disease, electrocardiographic (ECG) ST-segment elevation (STE) is frequently seen during dobutamine stress echocardiography (DSE) in leads overlying previous transmural left ventricular (LV) myocardial infarction. The mechanism of occasional STE during DSE in LV region
Shin Lin et al.
Journal of the American Heart Association, 2(2), e000097-e000097 (2013-04-18)
Patients with a myocardial bridge (MB) and no significant obstructive coronary artery disease (CAD) may experience angina presumably from ischemia, but noninvasive assessment has been limited and the underlying mechanism poorly understood. This study seeks to correlate a novel exercise
E Bartha et al.
British journal of anaesthesia, 110(4), 545-553 (2013-01-01)
Patients with proximal femoral fracture (PFF) are at high risk of postoperative complications. Goal-directed haemodynamic treatment (GDHT) in other high-risk surgical patients reduces postoperative complications. We aimed to compare effects of GDHT and routine fluid treatment (RFT) on postoperative outcomes
Daniel Augustine et al.
Circulation research, 114(1), 109-113 (2013-10-22)
Microparticles are cell-derived membrane vesicles, relevant to a range of biological responses and known to be elevated in cardiovascular disease. To investigate microparticle release during cardiac stress and how this response differs in those with vascular disease. We measured a
Philipp Emanuel Bartko et al.
Circulation. Cardiovascular imaging, 6(2), 268-276 (2013-01-01)
Decision making in patients with low flow-low gradient aortic stenosis mainly depends on the actual stenosis severity and left ventricular function, which is of prognostic importance. We used 2-dimensional strain parameters measured by speckle tracking at rest and during dobutamine
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