BP1108

Berberine chloride

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : Berberine chloride form, Natural Yellow 18
• Formule empirique (notation de Hill): C₂₀H₁₈ClNO₄
• Numéro CAS: 633-65-8
• Poids moléculaire : 371.81
• Numéro C.I. (Colour Index): 75160
• Numéro Beilstein : 3836585
• Numéro MDL: MFCD00011939
• Code UNSPSC : 12352210
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: berberine
• Forme: solid
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: BP
• Application(s): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• Clé InChI: VKJGBAJNNALVAV-UHFFFAOYSA-M

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Berberine chloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Phellodendron Chinense Bark

Phellodendron Amurense Bark

Fluorescent stain for heparin in mast cells

Actions biochimiques/physiologiques

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

Conditionnement

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable