B1000000

Betamethasone

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone
• Formule empirique (notation de Hill): C₂₂H₂₉FO₅
• Numéro CAS: 378-44-9
• Poids moléculaire : 392.46
• Numéro MDL: MFCD00062969
• Code UNSPSC : 41116107
• ID de substance PubChem : 329773150
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: synthetic
• Qualité: pharmaceutical primary standard
• Agence: EP
• Famille d'API: betamethasone
• Conditionnement: pkg of 60 mg
• Fabricant/nom de marque: EDQM
• Conditions de stockage: protect from light
• Couleur: white
• Pf: 235-237 °C (lit.); 235.6 °C (456.1°F at 1013.0 hPa)
• Solubilité: water: slightly soluble 0.063 g/L at 37 °C
• Densité: 0.305 g/cm³ at 25 °C (77°F)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• Clé InChI: UREBDLICKHMUKA-DVTGEIKXSA-N
• Informations sur le gène: human ... NR3C1(2908)

Description

Description générale

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360FD,H373
• Conseils de prudence: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 1B - STOT RE 2
• Organes cibles: Liver,Kidney,Endocrine system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable