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δ-Tocotrienol

analytical standard

Synonyme(s) :

(R)-δ-Tocotrienol, 8-Methyltocotrienol, [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol

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About This Item

Formule empirique (notation de Hill):
C27H40O2
Numéro CAS:
Poids moléculaire :
396.61
Numéro MDL:
Code UNSPSC :
85151701
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Source biologique

Elaeis guineensis

Niveau de qualité

Qualité

analytical standard

Pureté

≥97.0% (HPLC)

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Couleur

colorless to amber

Application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1

InChI

1S/C27H40O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1

Clé InChI

ODADKLYLWWCHNB-LDYBVBFYSA-N

Description générale

δ-Tocotrienol can be found in coconut oil, palm oil, and cereal grains such as barley, oats, wheat and rye.
δ-Tocotrienol is known as one of the homologs of Vitamin E.

Application

δ-Tocotrienol may be used as an analytical reference standard for the determination of δ-tocotrienol in:
  • Food samples of vegetable origin by high performance liquid chromatography-fluorescene detection (HPLC-FLD).
  • Chicken meat samples by LC-FLD.
  • Cereals by normal phase HPLC-FLD.
  • Rice bran samples by one-step equilibrium extraction method coupled to reversed-phase HPLC combined with dual wavelength ultraviolet-visible (UV-Vis) detector.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves


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Consulter la Bibliothèque de documents

A rapid procedure for analysing rice bran tocopherol, tocotrienol and gamma-oryzanol contents.
Chen MH and Bergman CJ
J. Food Compos. Anal., 18(2-3), 139-151 (2005)
Merriline M Satyamitra et al.
Radiation research, 175(6), 736-745 (2011-03-26)
δ-Tocotrienol (DT3), a vitamin E isoform, is associated with strong antioxidant and immunomodulatory properties. We confirmed the potent antioxidant activity in membrane systems and showed that DT3 is an effective radiation protector and mitigator. DT3 (4 μM, P < 0.001)
Pamela J Hodul et al.
PloS one, 8(2), e52526-e52526 (2013-02-09)
Vitamin E δ-tocotrienol has been shown to have antitumor activity, but the precise molecular mechanism by which it inhibits the proliferation of cancer cells remains unclear. Here, we demonstrated that δ-tocotrienol exerted significant cell growth inhibition pancreatic ductal cancer (PDCA)
N Zaiden et al.
Journal of atherosclerosis and thrombosis, 17(10), 1019-1032 (2010-08-13)
Present study aimed to elucidate the suppression of serum lipids by gamma- and delta-tocotrienol (γδT3). The lipid-lowering effects of γδT3 were investigated using HepG2 liver cell line, hypercholesterolemic mice and borderline-high cholesterol patients. In-vitro results demonstrated two modes of action.
Asaf A Qureshi et al.
Lipids in health and disease, 10, 239-239 (2011-12-22)
Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that proteasome inhibitors (dexamethasone, mevinolin, quercetin, δ-tocotrienol, and riboflavin) can inhibit lipopolysaccharide (LPS)-induced

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