69478

N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane

with 1% trimethylchlorosilane, for GC derivatization, LiChropur^™

• Formule empirique (notation de Hill) : C₆H₁₂F₃NOSi
• Numéro CAS: 24589-78-4
• Poids moléculaire : 199.25
• UNSPSC Code: 23151817
• PubChem Substance ID: 329761687
• NACRES: NA.22
• Beilstein/REAXYS Number: 1941550
• MDL number: MFCD00000411
• Assay: ≥97.0%
• Form: liquid

Propriétés

• Nom du produit: N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane, derivatization grade (GC derivatization), LiChropur^™
• grade: derivatization grade (GC derivatization)
• Quality Segment: 100
• assay: ≥97.0%
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Silylations
• technique(s): gas chromatography (GC): suitable
• refractive index: n20/D 1.378
• functional group: silyl
• SMILES string: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• InChI key: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Description

General description

Silylation can be performed by adding N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MTFA) during analysis of fluorometabolites via gas chromatography-mass spectrometry (GC-MS).

Application

Addition of Trimethylchlorosilane aids in the derivatization of amides, secondary amines and hindered hydroxy groups. Most volatile of the TMS derivatives often elutes at the solvent front of the GC.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mot-clé: Warning
• Codes de danger: H226,H315,H319,H335
• Mentions de précaution: P210 - P261 - P280 - P304 + P340 + P312 - P370 + P378 - P403 + P235
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Classe de stockage: 3 - Flammable liquids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): 78.8 °F - closed cup
• Point d'éclair (°C): 26 °C - closed cup
• EPI (équipement de protection individuelle): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter