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44112

Polysorbate 20

tested according to Ph. Eur.

Synonyme(s) :

Polysorbatum 20

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A propos de cet article

Numéro CAS:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:
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Quality Segment

agency

tested according to Ph. Eur.

description

non-ionic

form

liquid

mol wt

~1228 g/mol

CMC

0.06

transition temp

cloud point 76 °C

HLB

16.7

application(s)

research use (small molecule)

SMILES string

O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

Application


  • Evaluating a Modified High Purity Polysorbate 20 Designed to Reduce the Risk of Free Fatty Acid Particle Formation.: The research evaluates a modified high purity form of Polysorbate 20, designed to mitigate the formation of free fatty acid particles. This modification potentially enhances the stability and safety of biopharmaceutical formulations (Doshi et al., 2021).


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Cet article
1547925PHR3789Y0002464
description

tested according to Ph. Eur.

description

United States Pharmacopeia (USP) Reference Standard

description

certified reference material, pharmaceutical secondary standard

description

(European Pharmacopoeia (EP) Reference Standard)

form

liquid

form

-

form

-

form

-

application(s)

research use (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

pharmaceutical

CMC

0.06

CMC

-

CMC

-

CMC

-

mol wt

~1228 g/mol

mol wt

-

mol wt

-

mol wt

-

HLB

16.7

HLB

-

HLB

-

HLB

-

description

non-ionic

description

-

description

-

description

-


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Classe de stockage

10 - Combustible liquids

flash_point_f

527.0 °F - Pensky-Martens closed cup

flash_point_c

275 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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