39468

αAcide α-cyano-4-hydroxycinnamique

suitable for matrix substance for MALDI-MS, Ultra pure

• Synonyme(s) : αα-CCA, αα-CHCA, αα-Cyano, 4-HCCA, ACCA
• Formule linéaire : HOC₆H₄CH=C(CN)CO₂H
• Numéro CAS: 28166-41-8
• Poids moléculaire : 189.17
• UNSPSC Code: 41116105
• NACRES: NA.21
• PubChem Substance ID: 329755873
• EC Number: 248-879-1
• Beilstein/REAXYS Number: 3271427
• MDL number: MFCD00004204
• Form: solid

Propriétés

• Quality Segment: 100
• form: solid
• analyte chemical class(es): glycans, peptides, proteins
• technique(s): MALDI-MS: suitable
• mp: 245-250 °C
• solubility: methanol: 10 mg/mL, clear
• cation traces: Al: ≤1 mg/kg, Ba: ≤1 mg/kg, Ca: ≤1 mg/kg, Cd: ≤1 mg/kg, Co: ≤1 mg/kg, Cr: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤1 mg/kg, K: ≤1 mg/kg, Li: ≤1 mg/kg, Mg: ≤1 mg/kg, Mn: ≤1 mg/kg, Na: ≤1 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Sr: ≤1 mg/kg, Zn: ≤1 mg/kg
• suitability: suitable for matrix substance for MALDI-MS
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C(=C\c1ccc(O)cc1)C#N
• InChI: 1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
• InChI key: AFVLVVWMAFSXCK-VMPITWQZSA-N

Description

General description

α-Cyano-4-hydroxycinnamic acid (α-CHCA) functions as matrix and helps in facilitating ionization of proteins and peptides in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer.

Application

It was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H317
• Mentions de précaution: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1B
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves