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35394

Supelco

Albendazole sulfone

VETRANAL®, analytical standard

Synonyme(s) :

Methyl [5-(propylsulfonyl)-1H-benzimidazol-2-yl]carbamate

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About This Item

Formule empirique (notation de Hill):
C12H15N3O4S
Numéro CAS:
75184-71-3
Poids moléculaire :
297.33
Numéro Beilstein :
8394880
Numéro MDL:
MFCD00600775
Code UNSPSC :
41116107
ID de substance PubChem :
329755154
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CCCS(=O)(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

Clé InChI

CLSJYOLYMZNKJB-UHFFFAOYSA-N

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Description générale

Albendazole sulfone is a nonactive metabolite of albendazole sulfoxide (ABZSO).

Application

Albendazole sulfone may be used as a reference standard in the determination of albendazole sulfone in plasma samples using high-performance liquid chromatography (HPLC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazardEnvironment
GHS08,GHS09

Mention d'avertissement

Warning

Mentions de danger

H361d,H373,H410

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

Organes cibles

Adrenal gland,spleen,male reproductive organs,Blood

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCL4021
BCCH9379
BCCF2328
BCCC6525
BCCB7892

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Constant Edi et al.
PLoS neglected tropical diseases, 13(5), e0007325-e0007325 (2019-05-21)
A single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used for mass drug administration programs for
Simultaneous determination of albendazole sulfoxide enantiomers and albendazole sulfone in plasma.
Lanchote LV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 709(2), 273-279 (1998)
Zenaís Busatto et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 509-519 (2016-12-17)
This paper describes the development of analytical methods for the quantification of albendazole (ABZ) in fish feed and ABZ and its main known metabolites (albendazole sulfoxide, albendazole sulfone and albendazole aminosulfone) in fish fillet employing LC-MS/MS. In order to assess
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International journal for parasitology. Drugs and drug resistance, 7(2), 159-173 (2017-04-04)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for the pharmacological effect are unknown. We assessed
Victoria Miró et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(4), 408-414 (2019-07-16)
Combinations of bioactive phytochemicals with synthetic compounds have been suggested as promissory tools for the improvement of nematode control in livestock. Bioactive phytochemicals may interfere with the activity of drug-metabolizing enzymes and delay the metabolic conversion of anthelmintics into less
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