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247588

Sigma-Aldrich

Salicylic acid

ACS reagent, ≥99.0%

Synonyme(s) :

2-Hydroxybenzoic acid

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About This Item

Formule linéaire :
2-(HO)C6H4CO2H
Numéro CAS:
69-72-7
Poids moléculaire :
138.12
Beilstein:
774890
Numéro CE :
200-712-3
Numéro MDL:
MFCD00002439
Code UNSPSC :
12352100
ID de substance PubChem :
24854876
Nomenclature NACRES :
NA.21
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Qualité

ACS reagent

Niveau de qualité

200

Densité de vapeur

4.8 (vs air)

Pression de vapeur

1 mmHg ( 114 °C)

Essai

≥99.0%

Impuretés

H2SO4, passes test (darkened)

Résidus de calcination

≤0.01%

pb

211 °C (lit.)

Pf

158-161 °C (lit.)

Traces d'anions

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.003%

Traces de cations

Fe: ≤2 ppm
heavy metals (as Pb): ≤5 ppm

Groupe fonctionnel

carboxylic acid

Chaîne SMILES 

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

Clé InChI

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Informations sur le gène

human ... ALB(213) , PTPN1(5770)

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Description générale

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic.[1] Due to its keratolytic action, it is also used in topical ointments.[2]

Application

Salicylic acid has been used:
  • as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays[3]
  • as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)[4]

Actions biochimiques/physiologiques

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants.[5] It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.[6]

Pictogrammes

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H318,H361d

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

314.6 °F - closed cup

Point d'éclair (°C)

157 °C - closed cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
MKCV6094
MKCT5761
MKCR9026
MKCQ3890
MKCN7045

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SAFC

1.00635

Salicylic acid

Influence of cyclooxygenase-1 genotype on ex vivo aspirin response in patients at risk for stroke
Momary KM, et al.
Cerebrovascular Diseases (Basel, Switzerland), 27(6), 585-593 (2009)
Efficacy of salicylic acid to reduce Penicillium expansum inoculum and preserve apple fruits
da Rocha Neto AC, et al.
International Journal of Food Microbiology, 221, 54-60 (2016)
Xanthone
AF Holleman
Organic Syntheses, 1, 552-552 (1941)
Isochorismate synthase is required to synthesize salicylic acid for plant defence
Wildermuth MC, et al.
Nature, 414(6863), 562-562 (2001)
p-CHLOROPHENYL SALICYLATE
Norman GG and Kamath PM
Organic Syntheses, 4, 178-178 (1963)
Afficher tous les articles scientifiques apparentés

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Can I use this reagent for treatment of plantar wart?

    1 answer

    1. This product is intended for laboratory research purposes only. This product not to be used for any other purposes, including but not limited to, in vitro diagnostic purposes, in foods, drugs, medical devices or cosmetics for humans or animals or for commercial purposes.

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