07260

6-Aminohexanoic acid

≥98.5% (NT)

• Synonyme(s) : 6-Aminocaproic acid, 6-ACA, Aca, Acp, Aha, Ahx, acikaprin, afibrin, amicar, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
• Formule linéaire : H₂N(CH₂)₅CO₂H
• Numéro CAS: 60-32-2
• Poids moléculaire : 131.17
• UNSPSC Code: 12352202
• NACRES: NA.77
• PubChem Substance ID: 329748386
• EC Number: 200-469-3
• Beilstein/REAXYS Number: 906872
• MDL number: MFCD00008238

Propriétés

• Quality Segment: 200
• assay: ≥98.5% (NT)
• mp: 207-209 °C (dec.) (lit.)
• SMILES string: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• InChI key: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• Gene Information: human ... PLAT(5327), PLG(5340)

Description

General description

6-Aminohexanoic acid, or 6-aminocaproic acid, acts as an inhibitor of serine proteases. It shares structural similarities with the natural amino acid lysine but lacks an α-amino group.

Application

6-Aminohexanoic acid has been used as a component of the growth medium for tenogenic differentiation of mesenchymal stem cells. It has also been used in the preparation of modified graphene quantum dots.

Biochem/physiol Actions

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Other Notes

Improves solubilization of membrane proteins in electrophoresis

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: 404.6 - 408.2 °F
• flash_point_c: 207 - 209 °C
• ppe: dust mask type N95 (US), Eyeshields, Gloves