MABS419

Anti-BMPR-1A, clone 4B7B2 Antibody

ascites fluid, clone 4B7B2, from mouse

• Synonyme(s) : Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: ascites fluid
• Type de produit anticorps: primary antibodies
• Clone: 4B7B2, monoclonal
• Espèces réactives: mouse, human
• Technique(s): ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable; western blot: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P36894
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BMPR1A(657)

Description

Description générale

BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.

Immunogène

Purified recombinant fragment of human BMPR1A expressed in E. Coli

Application

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected BMPR-1A in colon cancer and kidney tissues.

Flow Cytometry Analysis: A 1;200-400 dilution from a representative lot detected BMPR-1A in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

Research Category
Signaling

Research Sub Category
Developmental Signaling

This Anti-BMPR-1A, clone 4B7B2 Antibody is validated for use in western blotting, IHC, flow cytometry & ELISA for the detection of BMPR-1A.

Qualité

Evaluated by Western Blotting in PC-3, K562 and mouse liver lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected BMPR-1A in PC-3, K562 and mouse liver lysates.

Description de la cible

~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Forme physique

Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.

Unpurified

Stockage et stabilité

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable