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HNDG4MAG-36K

Millipore

MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 4 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B.

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About This Item

Code UNSPSC :
12161503
eCl@ss :
32161000
Nomenclature NACRES :
NA.84

To order a Milliplex® kit, please search for your analyte of interest.

Niveau de qualité

Espèces réactives

human

Fabricant/nom de marque

Milliplex®

assay range

accuracy: 84-108%
standard curve range: 14-10,000 pg/mL
(S100B)

standard curve range: 21-15,000 pg/mL
(sRAGE)

standard curve range: 27-20,000 pg/mL
(Amyloid β42)

standard curve range: 3-2,500 pg/mL
(Amyloid β40)

standard curve range: 7-5,000 pg/mL
(GDNF)

Technique(s)

multiplexing: suitable

Méthode de détection

fluorometric (Luminex xMAP)

Conditions d'expédition

wet ice

Description générale

The MILLIPLEX® Human Neurodegenerative Bead Panel 4 is to be used for the simultaneous quantification of the following 5 analytes in any combination in human cerebrospinal fluid (CSF): S100B, Amyloid β40 (Aβ1-40), Amyloid β42 (Aβ1-42), sRAGE, and GDNF. This kit is not validated for testing serum or cell culture supernatants.

Panel Type: Neuroscience

Spécificité

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

  • Analytes: Amyloid β40, Amyloid β42, GDNF, sRAGE, S100B
  • Recommended Sample type: CSF
  • Recommended Sample dilution: 1:3
  • Assay Run Time: Overnight
  • Research Category: Neuroscience

Caractéristiques et avantages

Design your multiplex kit by choosing available analytes within this panel.

Conditionnement

Everything you need in a single kit.

Stockage et stabilité

Recommended storage for kit components is 2 - 8°C.

Autres remarques

Sensitivity: Refer to kit protocol for sensitivities of individual analytes.

Informations légales

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogrammes

Skull and crossbonesEnvironment

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Nicholas J Justice et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(6), 2612-2623 (2015-02-13)
Recent studies have found that those who suffer from posttraumatic stress disorder (PTSD) are more likely to experience dementia as they age, most often Alzheimer's disease (AD). These findings suggest that the symptoms of PTSD might have an exacerbating effect

Contenu apparenté

Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX® Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.

Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX® Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.

Neuroscience multiplex assays, such as MILLIPLEX® multiplex assays, enable simultaneous measurement of neuroscience-related biomarkers to gain a better picture of neurodegenerative diseases, neurological disorders, and neuropeptide/neurohormone signaling.

Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX® Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.

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Questions

1–2 of 2 Questions  
  1. Is the Milliplex Mouse Amyloid Beta Panel (MABMAG-83K) suitable for testing rat samples?

    1 answer
    1. Our R&D team conducted spike recovery and dilution linearity tests in rat serum samples. The sequence for both rat and mouse is identical. Although we attempted to develop this kit for both rat and mouse, the recovery in rats was considerably lower compared to mice. As a result, we do not recommend this kit for use with rats. Verification tests were not carried out in cerebrospinal fluid (CSF) or rat brain samples to assess potential improvement in recovery for other sample types.

      Helpful?

  2. What is the reason that GLP-1 total and active cannot be run together in HMHEMAG-34K?

    1 answer
    1. The same capture is used for both total and active GLP-1; however, the detection is specific to either total or active GLP-1.

      Helpful?

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