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CBL1345

Sigma-Aldrich

Anti-Integrin α2 Antibody, clone HMα2

clone HMalpha2, Chemicon®, from hamster(Armenian)

Synonyme(s) :

CD49b

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

hamster (Armenian)

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

HMalpha2, monoclonal

Espèces réactives

mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG

Numéro d'accès NCBI

NM_002203.3

Numéro d'accès UniProt

P17301

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGA2(3673)

Catégories apparentées

Description générale

The complex of CD49b associated with CD29 (integrin beta1) is a receptor for laminin and collagen. This complex is expressed by some CD4-positive T cells, natural killer cells, epithelial cells and platelets.

Spécificité

Specifically recognizes the 150 kDa mouse CD49b, also known as Integrin alpha2.

Application

Anti-Integrin α2 Antibody, clone HMα2 detects level of Integrin α2 & has been published & validated for use in FC, IF, IP, IH.
FlowCytometry: = .5 μg per 10e6 cells in 100 μL volume

Immunoprecipitation

Immunofluorescence

Immunohistochemistry

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Forme physique

Format: Purified
The affinity chromatography purified monoclonal is presented in phosphate buffered saline, pH 7.2, containing 0.09% sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Stockage et stabilité

Maintain at 2-8°C for up to 12 months from date of receipt.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Carlos H F Chan et al.
PloS one, 2(12), e1353-e1353 (2007-12-27)
CEA and CEACAM6 are immunoglobulin family intercellular adhesion molecules that are up-regulated without structural mutations in approximately 70% of human cancers. Results in in vitro systems showing tumorigenic effects for these molecules suggest that this correlation could indicate an instrumental
Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy.
Naser, et al.
Annals of the New York Academy of Sciences, 1516, 175-187 (2022)
Helena P Felgueiras et al.
Langmuir : the ACS journal of surfaces and colloids, 30(31), 9477-9483 (2014-07-24)
Functionalization of surfaces with poly(sodium styrenesulfonate) (poly(NaSS)) has recently been found to enhance osteointegration of implantable materials. Radical polymerization of poly(NaSS) on titanium (Ti)-based substrates has been used to improve their long-term performance by preventing fibrosis and consequently implant loosening.

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