8.52098

Fmoc-Glu(EDANS)-OH

≥95.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonyme(s) : Fmoc-Glu(EDANS)-OH
• Formule empirique (notation de Hill) : C₃₂H₃₁N₃O₈S
• Numéro CAS: 193475-66-0
• Poids moléculaire : 617.67
• MDL number: MFCD01076138
• UNSPSC Code: 12352209
• NACRES: NA.22

Propriétés

• Nom du produit: Fmoc-Glu(EDANS)-OH, Novabiochem^®
• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥95% (TLC), ≥95.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 15-25°C
• SMILES string: [S](=O)(=O)(O)c1c2c(c(ccc2)NCCNC(=O)CC[C@H](NC(=O)OCC3c4c(cccc4)c5c3cccc5)C(=O)O)ccc1
• InChI: 1S/C32H31N3O8S/c36-30(34-18-17-33-27-13-5-12-25-24(27)11-6-14-29(25)44(40,41)42)16-15-28(31(37)38)35-32(39)43-19-26-22-9-3-1-7-20(22)21-8-2-4-10-23(21)26/h1-14,26,28,33H,15-19H2,(H,34,36)(H,35,39)(H,37,38)(H,40,41,42)/t28-/m0/s1
• InChI key: HPYLYODKLGEPPX-NDEPHWFRSA-N

Description

General description

Fluorescence-labeled amino acid for preparing fluorescence-quenched peptide substrates by Fmoc SPPS ^[1]. Most frequently used in conjunction with Dabcyl quenching group.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Chromogenic Labeling of Synthetic Peptides

Literature references

^[1] J. W. Drijfhout, et al. in ′Peptides, Chemistry, Structure & Biology, Proc. 14th American Peptide Symposium′, P. T. P. Kaumaya & R. S. Hodges (Eds), Kingswinford, Mayflower Scientific Ltd., 1996, pp. 129.

Analysis Note

Colour (visual): slight grey to grey
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1238

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable