580221

Taurodeoxycholic Acid, Sodium Salt

Detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number: 6.

• Synonyme(s) : Taurodeoxycholic Acid, Sodium Salt, Sodium Taurodeoxycholate
• Formule empirique (notation de Hill) : C₂₆H₄₄NO₆S · Na
• Numéro CAS: 1180-95-6
• Poids moléculaire : 521.69
• MDL number: MFCD00003671
• UNSPSC Code: 41141802
• NACRES: NB.34

Propriétés

• Quality Segment: 100
• assay: ≥95% (TLC)
• form: solid
• mol wt: 521.28 g/mol
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• aggregation number: 6
• color: white
• pKa: 1.9
• CMC: 1 - 4 mM
• mp: 171 -175 °C
• solubility: water: 20 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: [Na+].[S](=O)(=O)([O-])OCCNC(=O)CCC(C1C2(C(C3C(C4(C(CC3O)CC(CC4)O)C)CC2)CC1)C)C
• InChI: 1S/C26H45NO7S.Na/c1-16(4-7-23(30)27-12-13-34-35(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1
• InChI key: XDQMFTUJGWFAGC-UHFFFAOYSA-M

Description

General description

Detergent useful for the solubilization of lipids and membrane-bound proteins (aggregation number: 6; CMC: 1-4 mM; pK_a: 1.9).

Application

• Microemulsion electrokinetic chromatography of corticosteroids: Effect of surfactants and cyclodextrins on the separation selectivity.: This study illustrates the application of taurodeoxycholic acid, sodium salt in chromatographic techniques, specifically enhancing the selectivity and efficiency of corticosteroid analyses, which is crucial for pharmaceutical quality control and research (Pomponio R et al., 2005).


• Modified micellar electrokinetic chromatography in the analysis of catechins and xanthines in chocolate.: Demonstrates the utility of taurodeoxycholic acid, sodium salt in improving the analysis of bioactive compounds in food products, facilitating better understanding of food composition and potential health benefits (Gotti R et al., 2004).


• Separation and determination of effective components in silymarin and preparations of silymarin by MECC.: This research uses taurodeoxycholic acid, sodium salt to enhance the micellar electrokinetic chromatography of silymarin, a milk thistle extract known for its liver-protective effects, underscoring the role of advanced analytical techniques in herbal medicine (Ding TM et al., 2000).

Packaging

Packaged under inert gas

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable