1.12130

Dimidium bromide

for surfactant tests

• Synonyme(s) : Dimidium bromide, 3,8-Diamino-5-methyl- 6-phenylphenanthridinium bromide
• Formule empirique (notation de Hill) : C₂₀H₁₈BrN₃
• Numéro CAS: 518-67-2
• Poids moléculaire : 380.28
• UNSPSC Code: 12352107
• EC Index Number: 208-256-7
• NACRES: NA.24
• MDL number: MFCD00011757

Propriétés

• Quality Segment: 200
• form: solid
• composition: dye content, ≥95% spectrophotometric assay
• loss: ≤5% loss on drying, 110°C
• mp: 242 °C
• bulk density: 380 kg/m³
• λmax: 523-528 nm in methanol
• storage temp.: 2-30°C
• SMILES string: Br.N1(C2=CC(=N)C=CC2=C3C(=C1c4ccccc4)C=C(C=C3)N)C
• InChI: 1S/C20H17N3.BrH/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13;/h2-12,22H,21H2,1H3;1H
• InChI key: MQOKYEROIFEEBH-UHFFFAOYSA-N

Description

Application

• A comparison of the base-pair specificities of three phenanthridine drugs using solution spectroscopy.: This study evaluates the specificity of three phenanthridine drugs, including Dimidium bromide, in binding to DNA base pairs through solution spectroscopy techniques. The research offers significant insights into the interactions at the molecular level, providing valuable information for chemists involved in drug design and DNA interaction studies (Dougherty G, 1982).

Analysis Note

Dye content (spectrophotometrically): ≥ 95 %
Identity (UV/VIS-Spectrum): passes test
Absorption maximum λ_max. (methanol): 523 - 528 nm
Spec. Absorptivity A 1%/1cm (λ_max; 0.0005 %; methanol): 168 - 177
TLC-Test: passes test
Loss on drying (110 °C): ≤ 5 %

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315 - H319 - H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable