1.10110

HEPES

Buffer substance HEPES EMPROVE^® EXPERT

• Synonyme(s) : Acide 4-(2-hydroxyéthyl)pipérazine-1-éthanesulfonique, Acide N-(2-hydroxyéthyl)pipérazine-N′-(2-éthanesulfonique)
• Formule empirique (notation de Hill): C₈H₁₈N₂O₄S
• Numéro CAS: 7365-45-9
• Poids moléculaire : 238.30
• Numéro Beilstein : 883043
• Numéro MDL: MFCD00006158
• Code UNSPSC : 12161703
• Numéro de classement CE : 230-907-9

Propriétés

• Niveau de qualité: 500
• Gamme de produits: EMPROVE^® EXPERT
• Puissance: >2000 mg/kg LD₅₀, oral (Rat)
• Caractéristiques: RNase and DNase free
• Technique(s): API processing | cocrystal formation: suitable
• pH: 5.0-5.5 (20 °C, 100 g/L in H₂O)
• Plage de pH utile: 6.8-8.2
• pKa (25 °C): 7.5
• Pf: 212.6 °C
• Solubilité: 703.6 g/L
• Densité: 1.44 g/cm³ at 20 °C
• Masse volumique apparente: 560 kg/m³
• Température de stockage: 2-25°C
• Chaîne SMILES: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• Clé InChI: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Description

Description générale

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable