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1.05175

Sigma-Aldrich

Hematoxylin solution modified acc. to Gill II

for microscopy

Synonyme(s) :

Hematoxylin solution acc. to GILL

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About This Item

Code UNSPSC :
41116113
Nomenclature NACRES :
NA.41

Niveau de qualité

Forme

liquid

IVD

for in vitro diagnostic use

pH

2.5 (25 °C in H2O)

Densité

1.04-1.06 g/cm3 at 20 °C

Application(s)

clinical testing
diagnostic assay manufacturing
hematology
histology

Température de stockage

15-25°C

Description générale

Hematoxylin solution modified acc. to Gill II - for microscopy, is used for human-medical cell diagnosis and serves the purpose of the cytological and histological investigation of sample material of human origin. It is a ready-to-use staining solution that when used together with other in vitro diagnostic products from our portfolio makes cytological target structures evaluable for diagnostic purposes in human gynecological and clinico-cytological specimen materials, for example cervical smears. In hematoxylin-eosin staining (H&E), the most widely used histological staining technique, nuclear staining is achieved using ready-to-use staining solutions, such as Mayer′s hemalum solution or Hematoxylin solution modified according to Gill II or Gill III. The dye is oxidized in a controlled manner, which renders the results robust and allows a brilliant differentiation of the stained structures. Counterstaining of i.e. for proteins, collagen, keratin, intercellular substances can be performed with alcoholic or aqueous Eosin Y solution 0.5 %.These solutions do need to be filtrated prior use.
A 500 ml bottle is sufficient for 1500 - 2500 slides. It is registered as IVD and certified as CE product. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Remarque sur l'analyse

Suitability for microscopy: passes test
Nuclei (Vaginal smear): blue to dark violet
Cyanophilic cytoplasm: bluish green to green
Eosinophilic cytoplasm: pink

Pictogrammes

Health hazardExclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral

Organes cibles

Kidney

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


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Andrea Sümegi et al.
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Wolcott-Rallison Syndrome (WRS) is a rare autosomal recessive disease that is the most common cause of neonatal diabetes in consanguineous families. WRS is caused by various genetic alterations of the Eukaryotic Translation Initiation Factor 2-Alpha Kinase 3 (EIF2AK3) gene. Genetic
Erzsébet Zavaczki et al.
Oxidative medicine and cellular longevity, 2020, 3721383-3721383 (2020-03-19)
Intraplaque hemorrhage frequently occurs in atherosclerotic plaques resulting in cell-free hemoglobin, which is oxidized to ferryl hemoglobin (FHb) in the highly oxidative environment. Osteoclast-like cells (OLCs) derived from macrophages signify a counterbalance mechanism for calcium deposition in atherosclerosis. Our aim

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