09-814

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

serum, from rabbit

• Synonyme(s) : dimethyl-arginine, asymmetric
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: polyclonal
• Species reactivity: mouse
• Application: WB
• Citations: 7

Propriétés

• biological source: rabbit
• Quality Segment: 100
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: mouse
• species reactivity (predicted by homology): rat (based on 100% sequence homology), human (based on 100% sequence homology)
• technique(s): western blot: suitable
• shipped in: wet ice
• target post-translational modification: unmodified

Description

General description

Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.

Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.

Immunogen

KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.

Application

Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.

Biochem/physiol Actions

This antibody recognizes dimethylated arginines.

Analysis Note

µ

Informations sur la sécurité

• Classe de stockage: 10 - Combustible liquids
• wgk: WGK 1