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Merck
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Key Documents

04-298

Sigma-Aldrich

Anti-IGF1 Receptor (CT) Antibody, clone 7G11

clone 7G11, Upstate®, from mouse

Synonyme(s) :

insulin-like growth factor 1

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

7G11, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Upstate®

Technique(s)

ELISA: suitable
western blot: suitable

Isotype

IgG1

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... IGF1(3479)

Spécificité

Recognizes C-terminus of IGF1 receptor

Immunogène

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C-terminus in human IGF1

Application

Anti-IGF1 Receptor (C-terminus) Antibody, clone 7G11 detects level of IGF1 Receptor (C-terminus) & has been published & validated for use in ELISA & WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualité

Routinely evaluated by immunoblot.

Description de la cible

90 kDa

Forme physique

100 &mciro;g of purified mouse monoclonal IgG lyophilized in 2X PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified
Subsequent thiophilic adsorption and size exclusion chromatography

Stockage et stabilité

2 years at -20°C from date of shipment. Reconstitute prior to use. Reconstitute with 1 mL H2O for 15 min at room temperature. Reconstituted aliquots should be stored frozen at -80°C. Thawed aliquots may be stored at 4°C for up to 3 months. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Remarque sur l'analyse

Control
Includes untreated A431 lysate as a positive control.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Thomas Thum et al.
Circulation research, 100(3), 434-443 (2007-01-20)
Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age
M Wallander et al.
Diabetologia, 49(10), 2247-2255 (2006-09-07)
Low levels of IGF-I are associated with increased risk of cardiovascular disease and type 2 diabetes. The aim of this study was to investigate the IGF-I system in patients with acute myocardial infarction (AMI) without previously known diabetes. One hundred
Marcus H Borges et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(9), 2411-2419 (2019-06-09)
We have previously described regulation of syncytial GLUT1 glucose transporters by IGF-I. Despite this, it is not clear what signal regulates transplacental glucose transport. In this report we asked whether changes in GLUT1 expression and glucose transport activity in diabetic
Shuhua Chen et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(4), 1813-1824 (2020-07-08)
Previous studies demonstrated that the endogenous neurosteroid allopregnanolone (Allo) promotes regeneration of rodent and human neural progenitor/neural stem cells (NSCs) in vitro and in vivo, and restores neurogenesis and cognitive function in the male triple transgenic mouse model of Alzheimer's
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