T-075

3,3′,5′-Triiodo-L-thyronine (Reverse T₃) solution

100 μg/mL in methanol with 0.1N NH₃, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonyme(s) : 3,3′,5′-Triiodo-L-thyronine, Reverse T₃, rT(3)
• Formule empirique (notation de Hill) : C₁₅H₁₂I₃NO₄
• Numéro CAS: 5817-39-0
• Poids moléculaire : 650.97
• NACRES: NA.24
• PubChem Substance ID: 329826619
• UNSPSC Code: 41116107
• MDL number: MFCD00036864

Propriétés

• grade: certified reference material
• Quality Segment: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol with 0.1N NH₃
• technique(s): gas chromatography (GC): suitable, liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: N[C@@H](Cc1ccc(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
• InChI: 1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1
• InChI key: HZCBWYNLGPIQRK-LBPRGKRZSA-N

Description

General description

Reverse T3, also known as rT3 or 3,3′,5′-Triiodo-L-thyronine, is a biologically inactive form of the thyroid hormone T3 and is produced in the body particularly during periods of stress. Under certain conditions such as fibromyalgia, liver disease, and chronic fatigue syndrome (CFS), more rT3 is produced which minimizes the desirable conversion of thyroxine (T4) to T3. Reverse T3 serum concentrations are measured by LC-MS/MS to monitor impact of these and other diseases on thyroid hormone levels.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370,H412
• pcodes: P210 - P273 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Classe de stockage: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup