T-006

(±)-11-nor-9-Carboxy-Δ⁹-THC solution

100 μg/mL in methanol, ampule of 1 mL, Cerilliant^®

• Formule empirique (notation de Hill): C₂₁H₂₈O₄
• Numéro CAS: 104874-50-2
• Poids moléculaire : 344.44
• Numéro CE : 200-659-6
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• drug control: psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): cannabis testing; forensics and toxicology
• Format: single component solution
• Température de stockage: 2-8°C
• Chaîne SMILES: CCCCCc1cc(O)c2C3C=C(CCC3C(C)(C)Oc2c1)C(O)=O
• InChI: 1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)
• Clé InChI: YOVRGSHRZRJTLZ-UHFFFAOYSA-N

Description

Description générale

11-nor-9-Carboxy-Δ⁹-THC, also known as THC acid, is the main secondary metabolite of Δ⁹-THC found in urine or blood of cannabis users. This certified reference solution is suitable as starting materials in the preparation of calibrators and controls for THC testing by GC/MS or LC/MS in forensic analysis, urine drug testing, or clinical toxicology.

Application

• Development and Validation of LC-HRMS for Cannabinoids in Whole Blood: This study introduces a liquid chromatography high-resolution mass spectrometry (LC-HRMS) method for quantifying cannabinoids, demonstrating its application in determining recent cannabis use, highlighting the relevance of THC metabolites like (±)-11-nor-9-Carboxy-Δ⁹-THC as analytical standards (DeGregorio et al., 2020).
• Enhanced LC-MS-MS Technique for Distinguishing Tetrahydrocannabinol Isomers: Research focused on an improved LC-MS-MS method capable of distinguishing Δ8- and Δ9-tetrahydrocannabinol isomers in biological specimens, pertinent for forensic toxicology using standards such as (±)-11-nor-9-Carboxy-Δ⁹-THC (Reber et al., 2022).
• Toxicogenetic Analysis of Δ9-THC-metabolizing Enzymes: This study explores the metabolism of THC, providing insights into the toxicogenetics of cannabinoid-metabolizing enzymes, relevant for drug metabolism studies using (±)-11-nor-9-Carboxy-Δ⁹-THC as a reference material (Gasse et al., 2020).

Autres remarques

Racemic mixture - not to be used for immunoassay

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup