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N-051

Supelco

Nalbuphine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C21H28ClNO4
Numéro CAS:
23277-43-2
Poids moléculaire :
393.90
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol (as free base)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

Cl.O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CCC6)c45

InChI

1S/C21H27NO4.ClH/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H/t15-,16+,19-,20-,21+;/m0./s1

Clé InChI

YZLZPSJXMWGIFH-BCXQGASESA-N

Informations sur le gène

human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

Description générale

A Snap-N-Spike® reference solution applicable for use in urine drug testing, pain prescription monitoring, clinical toxicology, forensic analysis, or pharmaceutical research by LC-MS/MS or GC/MS. Nalbuphine is a semisynthetic opioid analgesic sold under the trade name Nubain®. This painkiller is prescribed for the relief of moderate to severe pain.

Application


  • Development of a Thin-Layer Chromatography-Enzymatic Test Combination Method for the Isolation of α-Glucosidase Inhibitors From Thymelaea hirsuta.: Abid et al. (2022) combined thin-layer chromatography and enzymatic tests using Silica gel 60 TLC plates to isolate α-glucosidase inhibitors from Thymelaea hirsuta, showcasing a novel method for biochemical studies (Abid et al., 2022).

  • HPLC-UV and TLC-Densitometry Methods for Simultaneous Determination of Sofosbuvir and Daclatasvir: Application to Darvoni Tablet.: Fayed et al. (2022) utilized Silica gel 60 TLC plates in their TLC-densitometry method for the simultaneous determination of sofosbuvir and daclatasvir in pharmaceutical tablets, demonstrating the method′s application in pharmaceutical analysis (Fayed et al., 2022).


Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Nubain is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Vilnis Silins et al.
Paediatric anaesthesia, 22(3), 230-238 (2011-11-22)
Herniorraphy is a common surgical intervention in infants, particularly in those born prematurely. Prematurity and perioperative sedation have been shown to be risk factors for postoperative apnea. However, their influence upon PACU stay duration has not been evaluated. The goal
Vaginal delivery in a parturient excessively anticoagulated with fondaparinux.
N Hime et al.
International journal of obstetric anesthesia, 21(4), 385-387 (2012-08-25)
Anesteziologiia i reanimatologiia, (1)(1), 33-36 (2012-06-19)
We studied the changes in central and peripheral hemodynamic parameters under combined nubaine anesthesia during surgical interventions in children. The study was carried out at the stages of operation and anesthesia in 64 children at the age from 2 to
M A Smith et al.
Pharmacology, biochemistry, and behavior, 104, 40-46 (2013-01-12)
Sensitization refers to an increase in sensitivity to a drug and is believed to play a role in the etiology of substance use disorders. The purpose of the present study was to evaluate the ability of the mixed mu/kappa agonist
Robert Gear et al.
PloS one, 8(1), e50169-e50169 (2013-01-24)
Nalbuphine, an agonist-antagonist kappa-opioid, produces brief analgesia followed by enhanced pain/hyperalgesia in male postsurgical patients. However, it produces profound analgesia without pain enhancement when co-administration with low dose naloxone. To examine the effect of nalbuphine or nalbuphine plus naloxone on
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