L-911

Lorazepam-d₄ solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₁₅D₄H₆Cl₂N₂O₂
• Numéro CAS: 84344-15-0
• Poids moléculaire : 325.18
• Numéro CE : 200-835-2
• Numéro MDL: MFCD00673284
• Code UNSPSC : 41116107
• ID de substance PubChem : 329817668
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• Concentration: 1.0 mg/mL in acetonitrile
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: ClC1=CC=C2C(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3Cl)=NC(O)C(N2)=O)=C1
• InChI: 1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)/i1D,2D,3D,4D
• Clé InChI: DIWRORZWFLOCLC-RHQRLBAQSA-N

Description

Description générale

A stable-labeled internal standard suitable for quantitation of lorazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, or forensic analysis. Lorazepam, also known by trade names Ativan^® or Orfidal, is a benzodiazepine often prescribed for treatment of anxiety disorders.

Application

• Application in toxicological analysis: Lorazepam-d₄ was utilized as an analytical reference standard in a study aimed at the detection and quantification of lorazepam in human hair by GC-MS/NCI, assisting in forensic investigations related to traffic accidents (Cirimele et al., 1996).



• Confirmation of urinary benzodiazepine metabolites: A research paper detailed the use of Lorazepam-d₄ in GC-MS methodologies to confirm the presence of benzodiazepine metabolites in urine, providing crucial data for both clinical and forensic settings (Meatherall, 1994).

Informations légales

Ativan is a registered trademark of American Home Product Corp.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H312 + H332,H319
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 35.6 °F - closed cup
• Point d'éclair (°C): 2 °C - closed cup