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F-907

Supelco

Flunitrazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C16H12FN3O3
Numéro CAS:
1622-62-4
Poids moléculaire :
313.28
Numéro CE :
200-659-6
Numéro MDL:
MFCD00057906
Code UNSPSC :
41116107
ID de substance PubChem :
329799782
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CN(C1=CC=C([N+]([O-])=O)C=C1C(C2=CC=CC=C2F)=NC3)C3=O

InChI

1S/C16H12FN3O3/c1-19-14-7-6-10(20(22)23)8-12(14)16(18-9-15(19)21)11-4-2-3-5-13(11)17/h2-8H,9H2,1H3

Clé InChI

PPTYJKAXVCCBDU-UHFFFAOYSA-N

Informations sur le gène

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Description générale

A Certified Spiking Solution® suitable for use in GC/MS or LC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. Flunitrazepam is an intermediate-acting benzodiazepine marketed under the trade name Rohypnol as a hypnotic, sedative, anticonvulsant and skeletal muscle relaxant.

Application


  • Flunitrazepam Detection in Biological Samples: This study discusses the use of Intralipid as a matrix additive for evaluating hyperlipidemic postmortem blood, where Flunitrazepam can be detected and quantified. This is critical for toxicological analysis, contributing to pharmacological and forensic science (Elenstål et al., 2023).

  • Electrochemical Detection of Flunitrazepam in Beverages: An innovative approach to the rapid detection of Flunitrazepam, commonly known as a ′date rape′ drug, in spirits using a screen-printed sensor. This method is crucial for public health and safety, providing a quick and effective way to test beverages for contamination (Papadopoulos et al., 2020).



Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

A-911

7-Aminoflunitrazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-912

7-Aminoflunitrazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-921

7-Aminoflunitrazepam-d7 solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-925

7-Aminoflunitrazepam-d7 solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-905

Benzodiazepine Internal Standard-3 solution, 0.5-1.0 mg/mL in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant®

D-918

N-Desmethylflunitrazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-919

N-Desmethylflunitrazepam solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-925

N-Desmethylflunitrazepam-d4, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-915

Flunitrazepam-d7, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-140

3-Hydroxyflunitrazepam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

H-141

3-Hydroxyflunitrazepam-13C6 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

F-093

Flunitrazolam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

F-094

Flunitrazolam-13C2,15N solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

M A Mattila et al.
Drugs, 20(5), 353-374 (1980-11-01)
Flunitrazepam is a benzodiazepine derivative whose hypnotic effect predominates over the sedative, anxiolytic, muscle-relaxing and anticonvulsant effects characteristic of benzodiazepines. Thus, it is used as a night-time hypnotic and in anaesthesiology: due to the pronounced hypnotic effect it is not
Vanessa Pauly et al.
International clinical psychopharmacology, 26(5), 268-277 (2011-08-11)
Fourteen benzodiazepine (BZD) or BZD-like medications were analyzed with three data sources aiming to assess prescription drug abuse for the year 2008. After a descriptive analysis, a principal component analysis was carried out to explore correlations between seven indicators obtained
T Suzuki et al.
Endoscopy, 44(1), 38-42 (2011-12-07)
Studies have estimated that failure of cecal intubation occurs with conventional colonoscopy in up to 10 % of cases. Double-balloon endoscopy (DBE) systems, magnetic endoscope imaging (MEI), and transparent cap have been shown to improve success rates for colonoscopy. This study
Paul D'Aloise et al.
Science & justice : journal of the Forensic Science Society, 52(1), 2-8 (2012-02-14)
Desorption electrospray ionization-mass spectrometry (DESI-MS), a novel ambient ionization technique, was used in this study for determining flunitrazepam in various alcoholic beverages. Using this technique, no pretreatment of the samples was necessary and identification of the drug was accomplished in
Lisa R Gerak et al.
The Journal of pharmacology and experimental therapeutics, 340(3), 742-749 (2011-12-17)
Adverse effects of benzodiazepines limit their clinical use; these effects might be reduced without altering therapeutic effects by administering other positive GABA(A) modulators (i.e., neuroactive steroids) with benzodiazepines. One concern with this strategy involves reversing these combined effects in case
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