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850697C

Avanti

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, chloroform

Synonyme(s) :

PE(6:0/6:0)

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About This Item

Formule empirique (notation de Hill):
C17H34NO8P
Numéro CAS:
96893-06-0
Poids moléculaire :
411.43
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (850697C-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 850697C

Concentration

10 mg/mL (850697C-25mg)

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O

Catégories apparentées

Description générale

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) is a phosphoethanolamine (PE) molecule which carries short acyl chains. It is an ethanolamine-type substrate and a water-soluble phospholipid.

Application

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
  • as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity studies as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
  • as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
  • as calibration standard in hydrophilic interaction liquid chromatography (HILIC) and ion mobility (IM)

Actions biochimiques/physiologiques

Phosphoethanolamine (PE) is known to possess antitumor activity and inhibitory effects on tumor progression in vivo. It also exhibits antiproliferative and proapoptotic effects. It acts as a precursor of phosphatidylcholine and phosphatidylethanolamine.

Conditionnement

5 mL Clear Glass Sealed Ampule (850697C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Lipidomics by HILIC-Ion Mobility-Mass Spectrometry
Ion Mobility-Mass Spectrometry, 119-132 (2020)
Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry (2020)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
S F Martin et al.
Biochemistry, 39(12), 3410-3415 (2000-03-22)
The phosphatidylcholine-preferring phospholipase C from Bacillus cereus (PLC(Bc)) is a 28.5 kDa enzyme with three zinc ions in its active site. The roles that a number of amino acid residues play as zinc ligands and in binding and catalysis have
Shingo Mineta et al.
Journal of bioscience and bioengineering, 119(2), 123-130 (2014-08-20)
Streptomyces sanglieri extracellularly produces a glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP). The gene encoding the enzyme was found to consist of a 2124-bp ORF, which codes for an N-terminal 48 residue signal peptide required for secretion and a 660 amino acid mature protein

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