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Key Documents

850184P

Avanti

08:0 PI(3,5)P2

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt), powder

Synonyme(s) :

PIP2[3′,5′](8:0/8:0); 110664

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About This Item

Formule empirique (notation de Hill):
C25H58N3O19P3
Numéro CAS:
Poids moléculaire :
797.66
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 100 μg (with stopper and crimp cap (850184P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850184P-500ug))

Fabricant/nom de marque

Avanti Research - A Croda Brand 850184P

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]

Description générale

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is the least found phosphoinositides (PIs) and it accounts for approximately 0.05 to 0.1% of total cellular PI.

Actions biochimiques/physiologiques

Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) plays a key role in the embryonic development. It is very essential at postnatal stages. It is capable of activating ion channels on endosomes and lysosomes.

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-500ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Junya Hasegawa et al.
Cell structure and function, 42(1), 49-60 (2017-03-18)
In most eukaryotes, phosphoinositides (PIs) have crucial roles in multiple cellular functions. Although the cellular levels of phosphatidylinositol 5-phosphate (PI5P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) are extremely low relative to some other PIs, emerging evidence demonstrates that both lipids are crucial
Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Gerald R V Hammond et al.
Science (New York, N.Y.), 337(6095), 727-730 (2012-06-23)
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfills many cellular functions in the plasma membrane (PM), whereas its synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used a combination of pharmacological and chemical

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