700172P
Avanti
cholesterol-d6
Avanti Research™ - A Croda Brand, powder
Synonyme(s) :
cholesterol-d6
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About This Item
Produits recommandés
Pureté
>99% (TLC)
Forme
powder
Conditionnement
pkg of 1 × 10 mg (700172P-10mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand
Conditions d'expédition
dry ice
Température de stockage
−20°C
Description générale
Cholesterol-d6 is a deuterium labelled cholesterol. Ring labelled D6-cholesterol forms D6-steroidal glycoalkaloids (SGA).
Cholesterol-d6 is the deuterated cholesterol with deuteration in ring.
Application
Cholesterol-d6 is suitable for its use as a synthetic lipid standard, for cholesterol determination.
Cholesterol-d6 is used as a standard to detect cholesterol concentration using chromatography technique. It is also used to measure the percentage of cholesterol absorption by intravenously administrating into experimental animals.
Cholesterol-d6 may be used as an internal standard in
- electrospray ionization tandem mass spectrometry (ESIMS/MS)
- gas chromatography–mass spectrometry (GC-MS)
- for spiking lipid extracts from Drosophila for liquid chromatography–mass spectrometry (LC-MS)
Actions biochimiques/physiologiques
Cholesterol-d6 rich liposomes are used in understanding the kinetics of reverse cholesterol transport in lymphatic and aorta. It is used in the generation of stratum corneum (SC) lipid model systems for deuteration based neutron diffraction studies. Use of Cholesterol-d6 as a diet supplement has enabled the understanding cholesterol metabolism in the blood brain barrier.
Conditionnement
5 mL Amber Glass Screw Cap Vial (700172P-10mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Certificats d'analyse (COA)
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The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes
Testing, 4(7), 1075-1075 (2013)
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain
The Journal of Biological Chemistry, 289(34), 23712-23722 (2014)
Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue
Endocrinology, 150(1), 169-178 (2008)
JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
Nature Communications, 9(1), 3425-3425 (2018)
Biochemical membrane lipidomics during Drosophila development
Developmental Cell, 24(1), 98-111 (2013)
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