In this article, we demonstrate how an original effective "metal-free" and "chromatography-free" route for the synthesis of 3-thiocyanatopyrazolo[1,5-a]pyrimidines has been developed. It is based on electrooxidative (anodic) C-H thiocyanation of 5-aminopyrazoles by thiocyanate ion leading to 4-thiocyanato-5-aminopyrazoles (stage 1, yields
Jeffery, G.H. et al.
Vogel's Textbook of Quantitative Chemical Analysis, 170-170 (1989)
Amino-functionalized luminescent silica nanoparticles (LSNPs) doped with the europium(III) mixed complex, Eu(TTA)(3)phen with 2-thenoyltrifluoroacetone (TTA) and 1,10-phenanthroline(phen) were synthesized successfully using an revised Stöber method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR), and fluorescence spectroscopy were
Dicoumarol, a competitive inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), increases intracellular superoxide and affects cell growth of tumor cells. This work was set to establish a mechanistic link between dicoumarol, superoxide and cell cycle alterations in HL-60 cells. Using ES936
Cell death and differentiation, 18(2), 338-349 (2010-08-14)
The formation of reactive oxygen species (ROS) and the change of the intracellular pH (pH(i)) are common phenomena during apoptosis. How they are interconnected, however, is poorly understood. Here we show that numerous anticancer drugs and cytokines such as Fas
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
