QBD10406

MAL-dPEG^®₄-(m-dPEG^®₁₂)₃

• Synonyme(s) : Polyethylene glycol
• Formule empirique (notation de Hill): C₁₀₆H₂₀₂N₆O₅₀
• Numéro CAS: 1334178-05-0
• Poids moléculaire : 2360.75
• Code UNSPSC : 51171641
• ID de substance PubChem : 329823926
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90%
• Forme: solid or viscous liquid
• Pertinence de la réaction: reactivity: thiol reactive; reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive
• Architecture des polymères: shape: branched; functionality: monofunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: O=C(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O

Description

Caractéristiques et avantages

MAL-dPEG^®₄-(m-dPEG^®₁₂)₃ is a branched dPEG^® reagent which is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG^® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG^® branches. The numbers following dPEG^® are the exact number of repeat units in the linear chain. All of these dPEG^® products are hydrophilic, non-immunogenic, single molecular weight compounds. The maleimide functional group reacts rapidly and specifically with free sulfhydryls in aqueous media at pH 6.5-7.5.

Informations légales

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable