A88476

4-Methoxybenzoyl chloride

99%

• Synonyme(s) : 4-Anisoyl chloride, p-Anisoyl chloride
• Formule linéaire : CH₃OC₆H₄COCl
• Numéro CAS: 100-07-2
• Poids moléculaire : 170.59
• Numéro Beilstein : 471918
• Numéro CE : 202-816-4
• Numéro MDL: MFCD00000687
• Code UNSPSC : 12352100
• ID de substance PubChem : 24891375
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Pureté: 99%
• Forme: liquid
• Indice de réfraction: n20/D 1.581 (lit.)
• Point d'ébullition: 262-263 °C (lit.)
• Pf: 22 °C (lit.)
• Densité: 1.260 g/mL at 20 °C (lit.)
• Chaîne SMILES: COc1ccc(cc1)C(Cl)=O
• InChI: 1S/C8H7ClO2/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3
• Clé InChI: MXMOTZIXVICDSD-UHFFFAOYSA-N

Description

Description générale

4-Methoxybenzoyl chloride is one of the reactive acylating agents that can react with carboxylic acids, alcohols and amines to yield respective carboxylic anhydrides, esters and amides.

4-methoxybenzoyl chloride reacts with potassium thiocyanate to yield isothiocyanate derivative via nucleophilic addition-elimination mechanism.

Application

• 4-Methoxybenzoyl chloride can be used as radical precursor in visible-light photocatalysis to synthesize various heterocyclic compounds.
• It can be used to synthesize acylphosphine ligands for the rhodium-catalyzed hydrosilylation of alkenes.
• Incorporation of 4-methoxybenzoyl chloride modified indium tin oxide (ITO) as cathode for the fabrication of organic light-emitting diodes (OLEDs) has been reported.
• 1,3 diketones synthesized from 4-methoxybenzoyl chloride can be used in one pot synthesis of various pyrazole derivatives.
• It can also be used in the total synthesis of bioactive compounds like echinoside A and salinosporamide A.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H314
• Conseils de prudence: P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Classification des risques: Eye Dam. 1 - Skin Corr. 1B
• Risques supp: EUH014
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 188.6 °F - closed cup
• Point d'éclair (°C): 87 °C - closed cup
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter