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914304

Sigma-Aldrich

Hyaluronic acid methacrylate

average degree of substitution 35%, average Mw 175000

Synonyme(s) :

Functioanlized hyaluronic, HA methacrylamide, HAMA, Hyaluronic acid MA

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About This Item

Formule linéaire :
(NaC20H28NO15)n
Code UNSPSC :
12352106
Nomenclature NACRES :
NA.23

Description

NMR: Conforms to structure

Niveau de qualité

100

Forme

(powder or chunk(s) or fibers)

Poids mol.

average Mw 175000

Couleur

white to off-white

Température de stockage

2-8°C

Catégories apparentées

Application

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid and N-acetyl-D-glucosamine found primarily in connective tissues. HA based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug deliery applications. The methacrylate functionalized hyaluronic acid is photo-crosslinkable, and can be used to generate crosslinked hydrogels.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Cindy Chung et al.
Tissue engineering. Part A, 15(2), 243-254 (2009-02-06)
Mesenchymal stem cells (MSCs) are multipotent progenitor cells whose plasticity and self-renewal capacity have generated significant interest for applications in tissue engineering. The objective of this study was to investigate MSC chondrogenesis in photo-cross-linked hyaluronic acid (HA) hydrogels. Because HA
Judy Yeh et al.
Biomaterials, 27(31), 5391-5398 (2006-07-11)
Encapsulation of mammalian cells within hydrogels has great utility for a variety of applications ranging from tissue engineering to cell-based assays. In this work, we present a technique to encapsulate live cells in three-dimensional (3D) microscale hydrogels (microgels) of controlled
Bin Duan et al.
Acta biomaterialia, 9(8), 7640-7650 (2013-05-08)
Bioactive and biodegradable hydrogels that mimic the extracellular matrix and regulate valve interstitial cells (VIC) behavior are of great interest as three-dimensional (3-D) model systems for understanding mechanisms of valvular heart disease pathogenesis in vitro and the basis for regenerative
Liming Bian et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(25), 10117-10122 (2013-06-05)
Methacrylated hyaluronic acid (HA) hydrogels provide a backbone polymer with which mesenchymal stem cells (MSCs) can interact through several cell surface receptors that are expressed by MSCs, including CD44 and CD168. Previous studies showed that this 3D hydrogel environment supports
Aleksander Skardal et al.
Tissue engineering. Part A, 16(8), 2675-2685 (2010-04-15)
Bioprinting by the codeposition of cells and biomaterials is constrained by the availability of printable materials. Herein we describe a novel macromonomer, a new two-step photocrosslinking strategy, and the use of a simple rapid prototyping system to print a proof-of-concept

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Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

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