511129

1-Methylindole-2-carboxaldehyde

97%

• Synonyme(s) : 2-Formyl-1-methylindole, NSC 106285
• Formule empirique (notation de Hill) : C₁₀H₉NO
• Numéro CAS: 27421-51-8
• Poids moléculaire : 159.18
• NACRES: NA.22
• PubChem Substance ID: 24873423
• UNSPSC Code: 12352100
• MDL number: MFCD01863665
• Assay: 97%

Propriétés

• Quality Segment: 100
• assay: 97%
• mp: 81-85 °C (lit.)
• functional group: aldehyde
• SMILES string: Cn1c(C=O)cc2ccccc12
• InChI: 1S/C10H9NO/c1-11-9(7-12)6-8-4-2-3-5-10(8)11/h2-7H,1H3
• InChI key: IBNGPIOSWCMJGG-UHFFFAOYSA-N

Description

Application

1-Methylindole-2-carboxaldehyde may be used in the synthesis of indole-based melatonin analog hydrazone derivatives and (E)-5-((benzyloxy)methyl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-3-((1-methyl-1H-indol-2-yl)methylene)dihydrofuran-2(3H)-one.

Reactant for preparation of:

• Deazapurine isosteres from acylindoles via pyridine ring annulation
• 2,4-dichlorocinnamohydroxamic acid analogs for enhancing pharmacokinetics of botulinum neurotoxin serotype A protease inhibitors
• Tetrahydrocarbazoles via organocatalytic cascade Friedel-Crafts alkylation/Michael addition/aromatization reaction
• Azides, imines and amines via flow processes of amines and trimethylsilyl azide and aza-Wittig reaction
• 3-indolylpyridinedicarbonitriles as anti-inflammatory agents
• Bis(indolyl)methanes as antimicrobial and antioxidant agents

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H315,H319,H335
• Mentions de précaution: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves