394238

Pyrrolidine

≥99.5%, purified by redistillation

• Synonyme(s) : Tetrahydropyrrole, Tetramethyleneimine
• Formule empirique (notation de Hill): C₄H₉N
• Numéro CAS: 123-75-1
• Poids moléculaire : 71.12
• Numéro Beilstein : 102395
• Numéro CE : 204-648-7
• Numéro MDL: MFCD00005249
• Code UNSPSC : 12352100
• ID de substance PubChem : 24864581
• Nomenclature NACRES : NA.22

Propriétés

• Densité de vapeur: 2.45 (vs air)
• Niveau de qualité: 200
• Pression de vapeur: 128 mmHg ( 39 °C); 49 mmHg ( 20 °C)
• Pureté: ≥99.5%
• Forme: liquid
• Température d'inflammation spontanée: 653 °F
• Produit purifié par: redistillation
• Limite d'explosivité: 10.6 %
• Indice de réfraction: n20/D 1.443 (lit.)
• Solubilité: water: miscible
• Densité: 0.852 g/mL at 25 °C (lit.)
• Chaîne SMILES: C1CCNC1
• InChI: 1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2
• Clé InChI: RWRDLPDLKQPQOW-UHFFFAOYSA-N

Description

Description générale

Pyrrolidine is a five membered cyclic amine. It is a nitrogen heterocycle that forms the nucleus of various bioactive molecules. It can be synthesized by reacting 1,4-diaminobutanes with acids. It behaves as a strong base in employed in certain homogeneous nonaqueous reactions. Its crystalline structure has been investigated. Its reaction on the Ge(100)-2×1 surface and Si(100)-2×1 surface has been investigated. Pyrrolidine has been found to be one of the component of volatile amine fraction in the brewing process. A study on the kinetics of pyrrolidinolysis of phthalimide (PTH) shows second- and third-order terms in the rate law. Biodegradation of pyrrolidine by Mycobacterium strains has been studied.

Application

Pyrrolidine may be used in the following studies:

• Synthesis of pyrrolidine derivatives of pyrimidine.
• As a catalyst in the selective monoallylation of allylic alcohols.
• To capture carbondioxide in a bubble column reactor using pyrrolidine aqueous solutions by gas–liquid absorption.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H332,H314
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 37.4 °F - closed cup
• Point d'éclair (°C): 3 °C - closed cup
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter