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46323-U

Supelco

Aflatoxin B1 solution

3 μg/mL in benzene:acetonitrile (98:2), analytical standard

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About This Item

Empirical Formula (Hill Notation):
C17H12O6
CAS Number:
1162-65-8
Molecular Weight:
312.27
Beilstein:
1269174
MDL number:
MFCD00869647
UNSPSC Code:
85151701
PubChem Substance ID:
329757138

grade

analytical standard

packaging

ampule of 1 mL

concentration

3 μg/mL in benzene:acetonitrile (98:2)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

2-8°C

SMILES string

[H][C@]12OC=C[C@@]1([H])c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChI key

OQIQSTLJSLGHID-WNWIJWBNSA-N

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General description

Aflatoxin B1 (AFB1) is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. AFB1 is the most common in food and amongst the most potent genotoxic and carcinogenic aflatoxins. It is produced by both Aspergillus flavus and A. parasiticus.

Application

AFB1 solution was used as reference standard for the analysis of mycotoxins in paprika using LC-FD and LC-MS. AFB1 may be used as spiking standard solution to compare and determine AFB1 in corn and peanut samples using ultra-high-pressure liquid chromatography with UV detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 1A - Eye Irrit. 2 - Flam. Liq. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 1

Target Organs

Blood

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

12.2 °F - closed cup

Flash Point(C)

-11 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
LC14639V
LC10410
LC02610
LB97509
LB92973

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Aflatoxin M1 solution certified reference material, 10 μg/mL in acetonitrile, ampule of 1 mL

Supelco

CRM46319

Aflatoxin M1 solution

Zhaohui Fu et al.
Journal of chromatography. A, 1209(1-2), 271-274 (2008-10-07)
A rapid and simple method using ultra-high-pressure liquid chromatography with UV detection for the determination of aflatoxins B1, B2, G1 and G2 in corn and peanuts has been developed. In this method, aflatoxins were extracted with a mixture of acetonitrile
F Aguilar et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(18), 8586-8590 (1993-09-15)
Approximately half of hepatocellular carcinoma (HCC) from regions in the world with high contamination of food with the mycotoxin aflatoxin B1 (AFB1) contain a mutation in codon 249 of the p53 tumor suppressor gene. The mutation almost exclusively consists of
Ludmila V Roze et al.
Annual review of food science and technology, 4, 293-311 (2012-12-19)
Aflatoxins are among the principal mycotoxins that contaminate economically important food and feed crops. Aflatoxin B1 is the most potent naturally occurring carcinogen known and is also an immunosuppressant. Occurrence of aflatoxins in crops has vast economic and human health
J Miguel Hernández Hierro et al.
Journal of agricultural and food chemistry, 56(3), 751-756 (2008-01-22)
Aflatoxins are the only mycotoxins with legal limits for spices in the European Union. A further limit for ochratoxin A is expected to be adopted soon. Thus, rapid simultaneous methods for quantifying the five mycotoxins are sought. Liquid extraction, immunoaffinity
Chaobo Li et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 52(9), 1129-1136 (2012-12-15)
Aflatoxins are toxic and carcinogenic fungal metabolites. The aim of this research was to isolate aflatoxin B1 (AFB1)-degrading bacteria. Samples from various sources were screened by using coumarin as the sole carbon source. The strains that could grow in the
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